Fig. 3

The user interface of the SRS optimal parameters simulation is shown in Figure S3. The power input was 24.7 mW for the carrier and 14.6 mW for the probe on the sample, respectively. Pixel dwell time was set to 10 μs. A visualization of the signal response through the simulated system of a CNR optimized case, excluding the noise, is shown in (a) for a single object size of 1 μm and in (b) for an object size of 20 μm. In (c) and (d) a simulation is shown for a dense sample with an object size of 1 μm and 20 μm, respectively. The object size represents the half period distance of the spatial modulation, (i.e. it accounts for both the particle and the gap between particles in a dense sample)